Mesothelioma is cancer that attacks the mesothelium, the thin layer of tissue that covered the whole internal organs. Some of the organs that have the mesothelium, among others, the lungs (pleura), stomach (abdominal), heart (pericardial), and testicles (tunica vaginitis). Cancer is quite aggressive, and many sufferers are not successfully treated.
Mesothelioma most often affects the lungs (pleural mesothelioma) and the chest wall. Another type of mesothelioma is much less common is peritoneal mesothelioma, which attacks the mesothelium which the abdominal cavity. Mesothelioma is different from the conditions of benign mesothelioma in the chest which is also called the solitary fibrous tumour.
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Mesothelioma is a type of cancer that affects the mesothelial cells. This cell that wraps most of the organs in the human body.by wrapping it formed a blanket that protects the mesothelium. This mesothelium makes fluid that moves freely organ. Mesothelioma that affects many people is pleural mesothelioma which is located in the chest. while the least is called peritoneal mesothelioma located in the stomach (abdomen) Tumour that develops in the mesothelium there that can be raised and can not be removed. For tumours that can be removed (benign), surgery is usually done to provide treatment.
Pleural mesothelioma is most prevalent of all cases of mesothelioma (80% of cases) and asbestos is believed to be one of the causes of pleural mesothelioma. Asbestos broadly divided into two groups: serpentine and amphibole, each of which consists of several types of asbestos. Type blue crocidolite asbestos of amphibole group are the most common type of mesothelioma cause. Natural fibres such as erionite can also result in mesothelioma occur. In the past, there is a presumption that simian virus 40 (SV40) serves as the causative agent of mesothelioma but recent research has denied its role.
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Mesothelioma clinical symptoms are not typical, common complaints are often felt theclaustrophobic patient is accompanied by chest wall pain. Most patients do not complain of any symptoms and radiological abnormalities found by abnormalities during routine medical examination. Shortness tends to be progressive as a result of the accumulation of pleural fluid, pleural thickening, restrictive and comorbid disorders such as chronic obstructive pulmonary disease (COPD) and heart disease. Other accompanying symptoms that are frequent complaints are weak, night sweats and weight loss. This symptom appears on the condition of advance and is associated with poor prognosis. Other clinical manifestations depending on the location of the tumour metastasis. Not infrequently reported with painful swallowing, superior vena cava syndrome, Horner’s syndrome, paralysis of the vocal cords and diaphragm to the cause of death is generally due to infection and respiratory failure.